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The 11 Best Bed Bug Spray of 2023 (And What to Look For)

Hand holding black bottle of bed bug spray inside a room

Bed bug sprays can be an effective and long-lasting solution to your bed bug problems, but not all of them are made the same way! For this reason, we’ve come up with a guide to the best bed bug sprays of 2023.

Bed bugs are a common household problem, causing discomfort and stress to many homeowners. One effective solution to this issue is the use of bed bug spray. This product is designed to exterminate these pests, providing relief and peace of mind to those affected.

Bed bug sprays are formulated with powerful ingredients that target and kill bed bugs on contact. They are a convenient and cost-effective way to handle an infestation, allowing you to regain control of your home without the need for professional extermination services.

However, not all bed bug sprays are created equal. It’s crucial to choose a product that is both safe and effective, ensuring that it will get rid of the bugs without causing harm to you or your family.

In this guide, I’ll go through the best bed bug sprays of 2023, including what you need to look for when choosing the right one for your living space!

What Are Bed Bug Sprays?

Bed bug sprays are specially formulated insecticides designed to eradicate bed bugs, tiny nocturnal pests that feed on human blood. These sprays are typically available in aerosol cans or bottles with spray nozzles and are a common tool in the fight against bed bug infestations.

Wooden table with bed bug spray

Photo Credit: Shutterstock.

The active ingredients in bed bug sprays can vary, but they often contain pyrethrins, pyrethroids, or other insecticide compounds. Some sprays also contain growth inhibitors that prevent bed bugs from maturing and reproducing.

Bed bug sprays are typically used by directly applying them to the areas where bed bugs are known to hide or travel, such as mattresses, bed frames, and cracks or crevices in walls and furniture. It’s important to follow the manufacturer’s instructions for use to ensure safety and effectiveness.

While bed bug sprays can be an effective part of a bed bug control strategy, they are usually not enough on their own to completely eliminate an infestation.

They are best used in combination with other control methods, such as heat treatments, mattress encasements, and professional pest control services.

Do Bed Bug Sprays Really Work?

Yes, bed bug sprays do work, but their efficiency depends on various factors.

Bed bugs, like many other insects, can become resistant to certain pesticides, such as pyrethroids. Therefore, it’s crucial to select a spray with a formula designed to kill pyrethroid-resistant bed bugs.

Closeup shot of a bed bug colony in a mattress

Photo Credit: Shutterstock.

Bed bug infestations often hide in hard-to-reach places like the seams and tufts of your mattress, the cracks and crevices of your bed frame, behind headboards, in closets, and along the edges of carpets and floorboards.

A spray with a precise nozzle can help reach these hiding spots, but remember that sprays are not always sufficient to deal with heavy infestations.

Bed bug eggs are another concern. These are often tucked away in folds and cracks, and many sprays are not effective against them. Therefore, a comprehensive pest control plan should also include thorough cleaning of bed linens and regular vacuuming, especially around beds and furniture.

Finally, always follow the spray’s disposal instructions to ensure the safety of your pets and avoid potential harm to the environment.

So, while sprays can be a useful tool in the fight against bed bugs, they are just one part of an effective pest control strategy.

What To Look For In A Bed Bug Spray

When dealing with a bed bug infestation, choosing the right spray can make all the difference. But what exactly should you be looking for in a bed bug spray? Here are some key factors to consider:


Most sprays are made with potent insecticides to take control of a bed bug infestation.

Pyrethroids should be avoided, though, as they are no longer thought to be effective bed bug treatments on their own. Look for bed bug sprays that have undergone recent testing and have published research you can review.

You should always take precautions to protect children and pets, and if that is a concern, bed bug sprays with plant-based ingredients may be a better option for you.

Man mixing ingredients in a blue gallon for bed bug spray

Photo Credit: Shutterstock.

The most common method relies on aromatic oils, which, while some have a repellent effect, only work when they come into direct contact with the insect.

For this reason, it’s also important to thoroughly wash your hands with soap and water after handling any spray, especially before eating, drinking, chewing gum, using tobacco, or using the toilet. Toss the empty spray in the trash afterward to prevent accidental exposure.


Bed bug sprays start working as soon as you pull the trigger. Depending on whether the spray is a residual formula, an insect that comes into contact with it will either be instantly killed or spread the treatment to its relatives.

The ability to remain active after use is referred to as effectiveness. Most have a two-week effective window, but some, like the dust mentioned above, have a longer window.

Contact vs. Residuals

Sprays for bed bugs are typically offered in contact or residual formulations.

As the name implies, contact bed bug spray kills bed bugs when it comes into direct contact with them. This type works best on areas that you are sure have bed bug activity.

The majority are effective for two weeks, but keep in mind that they require direct contact with bugs to work.

Worker spraying the bed to exterminate bed bugs

Photo Credit: Shutterstock.

The best options for larger infestations or if you do not know where the bed bugs are currently residing are residual bed bug sprays. The treatment does not immediately kill the bugs; instead, the bugs are more likely to slowly spread the infection to other individuals in their group.

Even though residual means you might have to wait longer for results, it still contributes to reducing the severity of your infestation.

11 Best Bed Bug Sprays In2023

Whether you are dealing with a minor infestation or a full-blown bug crisis, there’s a spray for you on this list. These sprays are not only effective but also easy to use, ensuring that you can handle the situation quickly and efficiently.

Let’s look at the 11 best bed bug sprays of 2023:

1. Best Overall Bed Bug Spray: Ortho Home Defense Max Bed Bug Killer

Man spraying Ortho Home Defense Max Bed Bug Killer on bed

Ortho Home Defense Max Bed Bug Killer – Photo Credit: Amazon.

When it comes to the best overall bed bug spray, the Ortho Home Defense Max Bed Bug Killer stands out among the rest.

This highly effective spray is not only potent against bed bugs but also their eggs, ensuring a comprehensive solution to your infestation problems. What makes it the best is its fast-acting formula that begins to work immediately upon contact.

One strategy for easing the stress of a bed bug infestation is to use the product’s battery-operated wand option, which makes it usable almost anywhere. You can reach hard-to-reach areas like the edges of curtains, behind mattresses, and under furniture because it sprays more evenly than other techniques.

This spray is unscented and made specifically for indoor use. It can be directly applied to visible bugs and their eggs. Ortho advises reapplying every two weeks until the pests are gone if you still see them or their eggs.

This fast-acting spray also made it to the top of our list because it works on not only bed bugs but also fleas, ticks, ants, spiders, dust mites, and other insects. You can also apply it as a spot spray to carpets, closets, baseboards, and floor coverings.

2. Best Eco-Friendly Spray: Eco Defense Bed Bug Killer

Eco Defense Bed Bug Killer which kills bed bugs at every stage of life

Eco Defense Bed Bug Killer – Photo Credit: Amazon.

If you’re on the hunt for a solution to your bed bug problem, look no further than the Eco Defense Bed Bug Killer.

This eco-friendly spray tops our list of recommendations, and for good reason. Crafted from entirely natural, non-toxic ingredients, it’s a safe and effective choice for eliminating those pesky bed bugs.

The Eco Defense Bed Bug Killer stands out for its environmental friendliness. Unlike many other products on the market, this one doesn’t contain any harsh chemicals. Instead, it uses a unique blend of organic, bio-degradable ingredients that are harmless to humans and pets, but lethal to bed bugs.

What’s more, this spray is incredibly easy to use. Simply apply it to the affected areas, and you’ll see results in no time. It’s a fast-acting formula that penetrates the bugs’ exoskeleton and kills them on contact.

While the formula does have a distinct scent as a result of plant oils, I found it to be pleasant during testing, especially when compared to pesticides that are made of chemicals.

Since Eco-defense bed bug killer only kills on contact, a combination of strategies, such as good sanitation, is required to achieve the best results.

3. Best Budget Friendly Spray: Ecovenger Bed Bug Killer

Ecovenger Bed Bug Killer bottle

Ecovenger Bed Bug Killer – Photo Credit: Amazon.

If you’re on a budget, but want a solution that’s effective against bed bugs, then the travel-size Ecovenger Bed Bug Killer is your best bet.

This affordable spray is a powerhouse when it comes to eliminating these pesky critters. It’s not only budget-friendly but also environmentally friendly, making it a great choice for those who are conscious about their ecological footprint.

It costs less than $10 for the small 2-ounce size, which is ideal for traveling with. The majority of bed bug infestations in homes begin when travelers bring them back with them from other locations. By using this spray, you can prevent bugs from traveling home in your suitcase.

This mixture, which is made up of essential oils, kills on contact and keeps you safe while producing fantastic results. It also comes in 16-ounce and 128-ounce containers for those who prefer a bigger size.

4. Best For Large Spaces: Harris Bed Bug Killer

Yellow bottle of Harris Bed Bug Killer

Harris Bed Bug Killer – Photo Credit: Amazon.

When it comes to treating large spaces for bed bugs, the Harris Bed Bug Killer stands out as a top choice. This potent product is known for its long-lasting effect and broad coverage, making it ideal for extensive areas, such as hotels, dormitories, or large homes.

The Harris Bed Bug Killer boasts a powerful formula that kills bed bugs on contact, providing immediate relief from these pesky intruders. It also continues to kill bed bugs for up to sixteen weeks after the initial application, ensuring a long-term solution to your bed bug problems.

What sets the Harris Bed Bug Killer apart is its odorless and non-staining formula. This means you can apply it without worrying about unpleasant smells or stains on your furniture or bedding.

It’s also EPA registered and approved for indoor use, ensuring it’s safe for your family and pets. Plus, the handy wand will help you access those hard-to-reach areas where bedbugs may be hiding.

5. Best Foaming Spray: Raid Bed Bug Foaming Spray

Raid Bed Bug Foaming Spray purple container

Raid Bed Bug Foaming Spray – Photo Credit: Amazon.

When it comes to eliminating bed bugs, the Raid Bed Bug Foaming Spray stands out as the best foaming spray on the market. This product is specifically designed to kill bed bugs and their eggs, providing a comprehensive solution to your pest problem.

The key to its effectiveness lies in its unique foaming formula. Unlike regular sprays, the Raid Bed Bug Foaming Spray expands upon application, ensuring it reaches the nooks and crannies where these pests often hide.

This product also offers residual action, continuing to kill bugs for up to four weeks after application, making it a long-lasting solution for your home.

Not only is it potent, but it’s also easy to use. The foam expands into hard to reach indoor places, and is easy to see where you sprayed. This makes it easier to reach difficult areas like cracks, crevices, and behind furniture.

6. Best For Baseboards: Rockwell Cimexa Insecticide Dust

A bottle of Rockwell Cimexa Insecticide Dust

Rockwell Cimexa Insecticide Dust – Photo Credit: Amazon.

Although this is dust, we had to include it in our list since that’s what you need for baseboards. Spray may not provide the layer of penetration you need, but dusts most certainly do.

This insecticide dust is made from fine sicilia powder, which dries out the exoskeletons of bed bugs and eventually kills them. You can apply it using a paintbrush, and only a thin layer is required.

While the process might sound tedious, it’s well worth the hassle. This powerful insecticide is a potent solution for those pesky insects that love to make their home in the nooks and crannies of your house.

The key to its effectiveness is its residual action. Once applied, it continues to work for up to ten years, providing an ongoing barrier against insects. This makes it a cost-effective solution for homeowners who want to prevent infestations rather than dealing with them after they’ve taken hold.

The Rockwell Cimexa Insecticide Dust is a reliable, efficient, and user-friendly option for keeping your home pest-free.

7. Best For Upholstery: Say Bye Bugs Bed Bug Exterminator

White spray bottle of Say Bye Bugs Bed Bug Exterminator

Say Bye Bugs Bed Bug Exterminator – Photo Credit: Walmart.

When it comes to the best bed bug exterminator for upholstery, Say Bye Bugs deserves a special mention. This product has been specifically designed to eliminate bed bugs from your upholstery, offering an effective and immediate solution. It’s not just about eliminating the bugs, but also ensuring that they don’t make a comeback.

Say Bye Bugs Bed Bug Exterminator uses a unique formula that destroys bed bugs on contact, without causing any harm to your upholstery fabric. It’s easy to use and doesn’t leave any residue, making it a preferred choice for many homeowners.

Its non-toxic nature ensures the safety of your family members and pets, while its potent formula guarantees a bug-free environment. Say Bye Bugs is indeed a powerful weapon in your arsenal against these pesky intruders.

The product has garnered positive reviews for its efficiency, ease of use, and cost-effectiveness. With Say Bye Bugs Bed Bug Exterminator, you can rest assured that your upholstery is free from bed bugs and safe for everyone in your home. Say goodbye to bed bugs, and hello to a clean, comfortable living space.

8. Best Spot Treatment: Harris Bed Bug Killer

Harris Bed Bug Killer white spray bottle

Harris Bed Bug Killer – Photo Credit: Amazon.

When it comes to the most effective spot treatment for bed bugs, Harris Bed Bug Killer takes the top spot. This product is a favorite among homeowners for its efficiency and ease of use. It’s a pyrethroid resistant bed bug killer and comes in a handy, easy-to-use spray bottle.

Even the most obstinate bed bugs that have developed resistance to pesticides containing pyrethroids can be destroyed by this powerful formula. This bed bug spray stands out due to its ability to provide residual protection for up to 16 weeks.

Although Harris Pyrethroid Resistant Bed Bug Killer comes in a variety of shapes and sizes, I recommend the 32-ounce spray bottle for spot treatments because it is simple to use with just one hand.

Use this spray carefully because it does contain imidacloprid, which is toxic to both humans and animals.

9. Best Fast Acting Spray: Bedlam Plus

Gray bottle of Bedlam plus

Bedlam Plus – Photo Credit: Amazon.

Bedlam Plus is a top-tier choice when it comes to fast-acting sprays for pest control. This product is well-regarded for its potency and quick results, making it a popular choice among homeowners dealing with infestations.

Bedlam is among the most reputable brands in the fight against bed bugs, and this water-based spray is safe for use on the majority of surfaces, including your mattress. Additionally, it does not leave a lingering scent or leave stains on your upholstery.

The Bedlam Plus spray has a residual killing effect of up to two weeks and kills bed bugs immediately upon contact. It should be kept out of reach because, like many other options on this list, it is toxic.

10. Best Scented Spray: Mdx Concepts Bed Bug Killer

Mdx Concepts Bed Bug Killer Spray with peppermint leaves on the background

Mdx Concepts Bed Bug Killer – Photo Credit: Amazon.

There’s nothing more frustrating than a bed bug infestation, but thankfully, Mdx Concepts Bed Bug Killer is here to save the day. This product stands out as the best scented spray, offering an effective solution to your bug problem while leaving a pleasant aroma in your space.

Unlike many other chemical-laden products that leave a harsh, unpleasant smell, Mdx Concepts Bed Bug Killer is infused with natural essential oils like peppermint oil and comes with a candy-cane scent. This not only makes it safer for your household, but also leaves behind a refreshing scent that makes your home feel clean and bug-free.

Despite its gentle aroma, don’t underestimate its power. This bed bug killer is potent and fast-acting, capable of eliminating bugs upon contact. Its non-toxic formula ensures it’s safe for use around children and pets, making it an ideal choice for households.

11. Best Natural Alternative: Proof Bed Bug Spray

Proof Bed Bug Spray bottle

Proof Bed Bug Spray – Photo Credit: Amazon.

If you’re in search of a natural solution to your bed bug problem, then Proof Bed Bug Spray is your best bet.

This eco-friendly product uses 5.5% cold-pressed neem oil, a natural pesticide, to effectively eliminate bed bugs. Unlike many chemical-based sprays, Proof Bed Bug Spray doesn’t leave any harmful residue.

The spray is not only lethal to bed bugs but is also effective against their eggs, ensuring a thorough extermination. Its formula is designed to penetrate into cracks and crevices, reaching bed bugs wherever they hide.

Although it’s a powerful bug killer, Proof Bed Bug Spray is safe for use around children and pets, making it a perfect choice for households. With its natural ingredients and potent formula, it’s a reliable alternative to traditional pesticides. So, if you’re looking for an eco-friendly, effective solution to your bed bug problem, Proof Bed Bug Spray is the answer.


Other Bed Bug Guides from Planet Natural:

What Kills Bed Bugs Instantly? (The Complete Guide for 2023)

What Causes Bed Bugs? (Top 7 Causes of Bed Bug Infestations)

How to Get Rid of Bed Bugs on Mattress: Proven Solutions

Bed Bug Bites: Pictures, Symptoms, Treatment, and Prevention

What Do Bed Bug Eggs Look Like? Complete Guide with Pictures

Baby Bed Bugs: How to Identify & Get Rid of Them – Photos + FAQ

Complete Guide to Bed Bug Traps (+ 3 Best Ones in 2023!)

8 Most Common Bugs That Look Like Bed Bugs (Complete Guide)

How to Get Rid of Bed Bugs: A Complete 7-Step Guide


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