The potato beetle is well known for its ability to develop resistance to many insecticides making it one of the most difficult garden pests to get rid of.
This is perhaps the most confusing thing about potato bugs because this term is used to refer to two different insects! The first is the Colorado potato beetle and the other is the Jerusalem cricket.
If you have an active infestation and your crops are suffering, the culprit is most like the first kind: the Colorado potato beetle (Leptinotarsa decemlineata).